Envisioning treating genetically-defined urinary tract malformations with viral vector-mediated gene therapy

• Samuel Wilson

Human urinary tract malformations may cause dysfunctional voiding, urosepsis and kidney failure. Different affected people, with extreme phenotypes on fetal ultrasound screening, endure elective termination. Presently, there exist no particular therapies that concentrate on the first organic illness mechanisms that generate these urinary tract malformations. Traditionally, the pathogenesis of human urinary tract malformations has been…