lcabie

Mosaic Recombinant Adeno-associated Virus Vector rAAV/DJ/CAG for Targeted Gene Delivery to Melanoma Cells Metastasized to the Lung

 Background/intention: Sufferers with metastasized melanoma have restricted therapy choices and poor prognosis. Due to this fact, the event of therapies requires a brand new therapeutic method, of which gene remedy utilizing rAAV vectors may be proposed. The intention of the research was to look at the effectivity of the rAAV vector to transduce mouse melanoma cells…

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lcabie

Determining reliable parameter estimates for within-host and within-vector models of Zika virus

On this paper, we introduce three within-host and one within-vector fashions of Zika virus. The within-host fashions are the goal cell restricted mannequin, the goal cell restricted mannequin with pure killer (NK) cells class, and a within-host-within-fetus mannequin of a pregnant particular person. The within-vector mannequin consists of the Zika virus dynamics within the midgut…

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