lcabie

Generation of Motor Neurons from Human ESCs/iPSCs Using Sendai Virus Vectors

Human motor neurons are vital supplies for the analysis of the pathogenesis and drug discovery of motor neuron illnesses. Varied strategies to generate motor neurons (MNs) from embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) by the addition of signaling molecules have been reported. Nevertheless, they require a number of steps and sophisticated…

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lcabie

Modified Vaccinia Virus Ankara as a Viral Vector for Vaccine Candidates against Chikungunya Virus

There’s a must develop a extremely efficient vaccine in opposition to the rising chikungunya virus (CHIKV), a mosquito-borne Alphavirus that causes extreme illness in people consisting of acute febrile sickness, adopted by persistent debilitating polyarthralgia and polyarthritis. On this assessment, we offer a short historical past of the event of the primary poxvirus vaccines that led to…

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