lcabie

Pre-retinal delivery of recombinant adeno-associated virus vector significantly improves retinal transduction efficiency

Intravitreal injection is essentially the most extensively used injection method for ocular gene supply. Nevertheless, vector diffusion is attenuated by bodily boundaries and neutralizing antibodies within the vitreous. The 13-lined floor squirrel (13-LGS), as in people, has a bigger relative vitreous physique quantity than the extra widespread rodent fashions corresponding to rats and mice, which…

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lcabie

Vector competence of human-biting ticks Ixodes scapularis, Amblyomma americanum and Dermacentor variabilis for Powassan virus

Background: Powassan virus (POWV; genus Flavivirus) is the only real North American member of the tick-borne encephalitis sero-complex and an growing public well being risk within the USA. Maintained in nature by Ixodes spp. ticks, POWV has additionally been remoted from species of different laborious tick genera, but it’s unclear if these species can function vectors.…

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